Regulatory T-Lymphocytes

Qui-Gon Jinn representing a regulatory T-cell Qui-Gon Jinn was a Jedi who often tried to reign in the enthusiasm of his Padewan, regulating his behaviour. He also acted against Darth Tyranus (Th17 cell) opposing his actions.

Regulatory T-lymphocytes, also known as Tregs, are a subset of CD4+ T-lymphocytes. They play a key role in regulating and suppressing other immune cells.

Tregs suppress the activation, cytokine production and proliferation of CD4+ and CD8+ T-lymphocytes and are thought to also regulate B-lymphocytes and dendritic cells. They achieve this suppressive effect through the release of soluble chemical messengers with a regulatory function. Tregs help prevent an immune response to our own tissues, control the natural immune response to foreign substances and help prevent the development of autoimmune diseases.



Soluble Mediators